Sunday, July 26, 2009

Noni Extracts Can Protect Against Carcinogen-induced DNA damage in early Breast Cancer .

Investigators have identified several antibacterial, antiviral, anthelmintic, and antitumor effects of noni extracts. Among the claims made for noni today are potential benefits in lupus, diabetes, hypertension, drug addiction, AIDS, and cancer. Noni is also sold as a wellness drink.

One group of researchers at the University of Hawaii reported that the addition of noni to standard chemotherapeutic treatment with doxorubicin, cisplatin, 5-fluorouracil, and vincristine in the Lewis lung carcinoma mouse model resulted in the stimulation of multiple mediators, including tumor necrosis factor-[alpha], various interleukins, and nitric oxide, as well as improved survival time (Phytother. Res. 1999;13:380-7).

Noni juice has also been shown to be protective against carcinogen-induced DNA damage in early breast cancer in animal models and, in one small study, to lower plasma levels of lipid peroxides and superoxide anion radicals in cigarette smokers (Acta Pharmacol. Sin. 2002;23:1127-41). A phase I study, sponsored by the National Center for Complementary and Alternative Medicine and conducted at the University of Hawaii Cancer Research Center, is currently enrolling patients.

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VIDEO TELL THE INGREDIENT OF NONI FRUIT:

Dr. Ralph Heinicke pioneered the study of the alkaloid Xeronine. Xeronine is produce in the body from the building blocks Proxeronine and Proxeronase. These building blocks are abundant in the juice of the Morinda citrifolia fruit.
Xeronine is a relatively small alkaloid that is physiologically active in the picogram range. (Editorial note: a picogram is one trillionth of a gram.) It occurs in practically all healthy cells of plants, animals and microorganisms. However, the amount of free alkaloid is minute, and is well below the limits of normal chemical analytical techniques.